What is in NUTRAGESIC Nerve Health?
The constituent ingredients in NUTRAGESIC include:
Vitamin B12 (Methylcobalamin) is a water-soluble vitamin that is essential for the normal functioning of the brain and nervous system. Vitamin B12 is important in the synthesis and maintenance of myelin, fatty sheaths that wrap around nerves and are essential for proper transmission of nerve impulses. Vitamin B12 deficiency can result in peripheral neuropathy resulting in a disruption in nerve impulse propagation.
Vitamin B6 (Pyridoxine) helps the body metabolize fats and proteins, and facilitates the conversion of carbohydrates into fuel (glucose), which is used to produce energy. Vitamin B6 is essential for proper nerve function. It is used by the body to make several neurotransmitters, chemicals that carry signals from one nerve cell to another. In adults, neuropathy due to B6 deficiency starts with numbness, paresthesias, or burning pain in the feet which then ascends to affect the legs and eventually the hands. Vitamin B6 supplementation has been used to treat peripheral neuropathy and polyneuropathy due to Vitamin B6 deficiency.
Folate (Quatrefolic (6S)-5 Methyltetrahydrofolic Acid) is a unique form of the folate, another B-Vitamin that is essential for the proper functioning of peripheral nerves. Unlike supplementary folic acid which requires enzymatic activation before it can be used by the body, (6S)-5-MTHF is able to penetrate the cell without requiring metabolism. This bioactive form of folate is seven times more bioavailable than folic acid, and has been shown to improve microvascular blood flow to peripheral nerves.
Benfotiamine, found to be a worthy adjuvant in the management of diabetic and peripheral neuropathy, is a fat soluble analogue of the vitamin Thiamine (B1). This compound has been found to help ameliorate pain from peripheral neuropathy, including neuropathy due to diabetes. Benfotiamine reduces the proliferation of metabolites that contribute to the damage of micro vessels in the diabetic patient. The pathology of microvasculature damage is seen in diabetic retinopathy, nephropathy, and neuropathy.
Alpha-Lipoic Acid (ALA) is a powerful antioxidant. Antioxidants help protect cells from damage by attacking “free radicals”, waste products created when the body turns food into energy. ALA helps reduce hyperglycemia induced free radical formation. This ability to decrease free radicals is thought to help patients with diabetic peripheral neuropathy whose symptoms include pain, numbness, burning, and tingling in the arms and legs. ALA may not only serve as an analgesic treatment for peripheral neuropathic pain, but may also improve nerve function. Furthermore, taking alpha-lipoic acid may help another diabetes-related condition called autonomic neuropathy, which affects nerves to internal organs.